Preventing the rise in mortality rates demands a multi-pronged strategy including health education, improved access to healthcare, public health initiatives, addressing inequalities, emergency services enhancement, and mental health support. Ensuring affordability and availability of medication involves measures like price regulations, promoting generic drugs, negotiating with pharmaceutical companies, international collaboration, research funding, health insurance expansion, telemedicine adoption, pharmacy benefit programs, non-profit initiatives, and advocacy efforts. A comprehensive approach involving government, healthcare entities, pharmaceutical firms, non-profits, and communities is necessary to effectively combat mortality increase and make essential medications accessible to all.